General Cell Based Assays
Cayman Chemical D-Fructose-1,6-bisphosphate (sodium salt hydrate), Purity: ≥95%, CAS: 81028-91-3, 1 g
An intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis
Abcam RG 108, non-nucleoside DNA methyltransferase inhibitor (DNMT), 50MG
MW 334.3 Da, Purity >99%. Novel, non-nucleoside DNA methyltransferase (DNMT) inhibitor, capable of interacting with the DNMT1 active site (IC₅₀ = 115 nM). Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes in vitro. Capable of enhancing the efficiency of induced pluripotent stem cell (iPS) generation.
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Matrix metalloproteinase-12 (MMP-12) fluorometric drug discovery kit, GREEN (1x96wells)
The MMP-12 Fluorometric (also known as fluorimetric) Drug Discovery Kit, GREEN is a complete assay system designed to screen MMP-12 inhibitors using a quenched fluorogenic OMNIMMP Green substrate: 5-FAM-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(TQ2W)-NH2 [5-FAM = 5-carboxyfluorescein; Nva=norvaline; TQ2W=quencher]. FAM fluorescence is thoroughly quenched by the TQ2W group until cleavage by MMPs separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-12, a potential therapeutic target. The compound NNGH is also included as a prototypic control inhibitor. Alternative name: Metalloelastase, Macrophage elastase. Applications: Fluorescent detection, HTS Activity assay.
Cayman Chemical 33-BCRP Inhibitor, Purity: ≥98%, CAS: 2953730-35-1, 10 mg
A BCRP inhibitor; sensitizes mitoxantrone-resistant H460/MX20 cells to mitoxantrone-induced cell death alone and in combination with UV radiation; sensitizes KB-C2 cells overexpressing P-gp to colchicine-induced cell death; increases intracellular accumulation of mitoxantrone in H460/MX20 cells at 5 µM
Eurofins Discoverx PathHunter Human YES1 Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human YES1 Stable Cell Line Kinase Activity Assay (U2OS) measures YES1 activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioss KD-Validated Catalase Rabbit R
Catalase Primary Antibody Unconjugated Public Immunogen Range 50-100/527 Host Species Rabbit Target Species Human Rat Clonality Monoclonal Applications WB IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Bioassay Systems EnzyChrom™ Catalase Assay Kit. For quantitative determination of catalase activity and evaluation of drug effects on catalase activity.
For quantitative determination of catalase activity and evaluation of drug effects on catalase activity. Key Features: Sensitive and accurate. Use 10 µL sample. Linear detection range 0.2 to 5 U/L catalase activity. Simple and Convenient. The procedure involves adding a Substrate to sample, incubation for 30 min, followed by a Detection Reagent and reading the optical density or fluorescence intensity. Method: OD570nm, or FL530/585nm. Samples: Serum, plasma, urine, saliva, cell culture etc. Species: All. Procedure: Assay takes 40 min. Kit size: 100 tests. Detection limit: 0.2 U/L.
Eurofins Discoverx cAMP Hunter™ Human GHRHR Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human GHRHR Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GHRHR (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.